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ESR 10 - Margot Delavy

Principal investigator: Marie-Elisabeth Bougnoux

Host institution: IP

ESR Project

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Influence of the microbiota on Candida albicans gastrointestinal colonization in healthy individuals

My name is Margot and I come from Switzerland, where I studied at the University of Lausanne (2014-2019). I obtained my Bachelor degree in Biology in 2017 and decided to enroll for a Master degree in Molecular Life Sciences with a specialization in Microbiology.

During my Master, I achieved a 3-months internship at the Department of Fundamental Microbiology (Lausanne, Switzerland) under the direction of Prof. Sara Mitri. There, I studied the interactions within a consortium four bacterial species with a view to bioremediation. This was followed by a 1-year internship at the Institute of Microbiology of the Lausanne University Hospital (Switzerland), where I completed my Master thesis under the supervision of Dr. Alix Coste and the co-direction of Prof. Gilbert Greub and Prof. Dominique Sanglard. During this year, I studied the use of Matrix-Assisted Laser-Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) to detect fluconazole resistance in the pathogenic fungus Candida albicans. This project, at the frontier between research and medical diagnostic, make me more interested in focusing my career in medical mycology; especially by working with C. albicans. At the end of my Master, I had the opportunity to stay in the lab for 4 extra months to complete the project with a focus in bioinformatics, particularly in machine-learning approaches. 

Since October 2019, I have been working as an early stage researcher (ESR) as part of the FunHoMic Marie Skłodowska–Curie Innovative Training Network at the Fungal Biology and Pathogenicity Unit at Institut Pasteur in Paris (France), under the direction of Prof. Marie-Elisabeth Bougnoux. Our project aims to decipher the influence of the microbiota on gastrointestinal colonization by C. albicans in healthy individuals.