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Objectives:

  • Screening of antimicrobial proteins to define the mechanism of action of Lcr35®.
  • Exploration of the mode-of-action of the identified anti-Candida compounds.
  • LBP and isolated antimicrobial proteins impact on host immunity in a Caenorhabditis elegans model.
  • Development of a new LBP optimizing the anti-Candida activity for intestinal and/or vaginal and other applications (topic, systemic).

Expected Results:

  • Determination of the anti-Candida molecule(s) secreted by Lcr35®
  • Understanding and characterization of the involved metabolic pathway
  • Development of LBP to promote this metabolic pathway and improve anti-Candida activity

 


 

PROJECT SUPERVISOR
Adrien Nivoliez

 

 

POSITION FILLED

 

Project Description